{"id":3027,"date":"2026-09-14T14:39:34","date_gmt":"2026-09-14T14:39:34","guid":{"rendered":"https:\/\/www.innothyrogen.eu\/uncategorized-sr\/druga-letnja-skola-innothyrogen-donosi-obuku-iz-genomike-i-gwas-a-u-beograd\/"},"modified":"2026-09-17T07:18:18","modified_gmt":"2026-09-17T07:18:18","slug":"druga-letnja-skola-innothyrogen-donosi-obuku-iz-genomike-i-gwas-a-u-beograd","status":"publish","type":"post","link":"https:\/\/www.innothyrogen.eu\/sr\/%d0%b2%d0%b5%d1%81%d1%82%d0%b8\/druga-letnja-skola-innothyrogen-donosi-obuku-iz-genomike-i-gwas-a-u-beograd\/","title":{"rendered":"Druga letnja \u0161kola InnoThyroGen donosi obuku iz genomike i GWAS-a u Beograd"},"content":{"rendered":"\n

Od 8. do 12. septembra 2026.<\/strong>, projekat InnoThyroGen odr\u017eao je svoju 2. letnju \u0161kolu<\/strong> na Institutu za molekularnu genetiku i geneti\u010dko in\u017eenjerstvo (IMGGE<\/a>) u Beogradu, Srbija.<\/p>\n\n

Tokom pet dana, u\u010desnici su istra\u017eivali klju\u010dne metode i alate koji se koriste u humanoj genetici i studijama asocijacije na nivou celog genoma (GWAS). Program je kombinovao predavanja, prakti\u010dne kompjuterske radionice, pozvana predavanja, grupne diskusije i interaktivne sesije. <\/p>\n\n

Letnja \u0161kola je postepeno prelazila sa fundamentalnih statisti\u010dkih i ra\u010dunarskih ve\u0161tina na napredne genomske analize. U\u010desnici su radili sa alatima i metodama koje se koriste u modernim geneti\u010dkim istra\u017eivanjima i imali su mnogo prilika da razgovaraju o svom radu sa predava\u010dima i drugim u\u010desnicima. <\/p>\n\n

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Dan 1 \u2013 Postavljanje temelja<\/h2>\n\n

Letnja \u0161kola je po\u010dela sa sesijom dobrodo\u0161lice i upoznavanja u\u010desnika<\/strong>, koja je predstavila program i pru\u017eila u\u010desnicima priliku da se me\u0111usobno upoznaju.<\/p>\n\n

Prva predavanja su se fokusirala na statisti\u010dke osnove potrebne za geneti\u010dke studije. Nikolina Plei\u0107<\/a><\/strong> je predstavila klju\u010dne statisti\u010dke koncepte kroz dvodelno predavanje Uvod u statistiku za geneti\u010dke studije<\/em>.<\/p>\n\n

Popodne su u\u010desnici pre\u0161li sa teorije na prakti\u010dan rad. Andrea Gelemanovi\u0107<\/a><\/strong> je vodila dve kompjuterske radionice o Linux-u. Sesije su obuhvatile kako osnovnu, tako i napredniju upotrebu Linux-a i pripremile u\u010desnike za ra\u010dunarski rad planiran za naredne dane. <\/p>\n\n

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Dan 2 \u2013 Humana genetika, GWAS i R<\/h2>\n\n

Drugi dan je u\u010desnike upoznao sa humanom genetikom i studijama asocijacije na nivou celog genoma<\/strong>.<\/p>\n\n

Andrea Gelemanovi\u0107 je otvorila dan predavanjem Uvod u humanu genetiku i GWAS<\/em>. Nikolina Plei\u0107 je zatim nastavila sa dve sesije o Statisti\u010dkim modelima za GWAS<\/em>. <\/p>\n\n

U\u010desnici su tako\u0111e oja\u010dali svoje prakti\u010dne ve\u0161tine analize podataka. Tokom dve kompjuterske radionice, Andrea Gelemanovi\u0107 je predstavila R<\/strong>, od po\u010detnog pode\u0161avanja i tipova podataka do manipulacije i vizualizacije podataka. <\/p>\n\n

Dan je zavr\u0161en grupnom diskusijom o Otvorenoj nauci, etici i metodolo\u0161kim zamkama u GWAS-u<\/strong>. Sesija je podstakla u\u010desnike da sagledaju \u0161ire metodolo\u0161ke i istra\u017eiva\u010dke izazove, izvan tehni\u010dke analize. <\/p>\n\n

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Dan 3 \u2013 Kontrola kvaliteta i populaciona struktura<\/h2>\n\n

Tre\u0107i dan je bio fokusiran na va\u017ene korake koje istra\u017eiva\u010di preduzimaju pre i tokom GWAS analiza.<\/p>\n\n

Nakon pozvanog predavanja Lennarta C. Karssena<\/strong> (PolyOmica<\/a>, Holandija), Andrea Gelemanovi\u0107 je u\u010desnike upoznala sa Kontrolom kvaliteta za GWAS<\/strong>. U\u010desnici su zatim primenili ove koncepte tokom prakti\u010dne radionice koriste\u0107i PLINK 2.0<\/strong>. <\/p>\n\n

Popodne je bilo fokusirano na populacionu strukturu<\/strong>. Nikolina Plei\u0107 je prvo predstavila temu kroz predavanje, a zatim je vodila u\u010desnike kroz prakti\u010dnu radionicu PLINK 2.0. <\/p>\n\n

Dan je zaklju\u010den predavanjem o Analizi asocijacije<\/strong>, pripremaju\u0107i u\u010desnike za naprednije analize \u010detvrtog dana.<\/p>\n\n

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Dan 4 \u2013 Od analize asocijacije do funkcionalne anotacije<\/h2>\n\n

\u010cetvrti dan je nastavljen sa naprednim GWAS metodama i njihovom prakti\u010dnom primenom.<\/p>\n\n

Program je po\u010deo pozvanim predavanjem Maksima Frejdina<\/strong> (King\u2019s College London<\/a>, Ujedinjeno Kraljevstvo). U\u010desnici su zatim radili na Analizi asocijacije<\/strong> koriste\u0107i PLINK 2.0 i GEMMA pod vo\u0111stvom Nikoline Plei\u0107. <\/p>\n\n

Slede\u0107a kompjuterska radionica bila je fokusirana na Funkcionalnu anotaciju<\/strong>. U\u010desnici su istra\u017eivali nekoliko \u0161iroko kori\u0161\u0107enih alata i resursa, uklju\u010duju\u0107i COLOC, FUMA, GTEx i LocusZoom. <\/p>\n\n

Popodne su pozvani \u010dlanovi u\u010destvovali u InnoThyroGen R&I laboratoriji<\/strong>. U me\u0111uvremenu, u\u010desnici Letnje \u0161kole imali su priliku da istra\u017ee Beograd kroz vo\u0111enu turu grada. <\/p>\n\n

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Dan 5 \u2013 Poligeni skorovi rizika i napredna genomika<\/h2>\n\n

Poslednji dan je okupio nekoliko naprednih pristupa u geneti\u010dkim istra\u017eivanjima.<\/p>\n\n

Andrea Gelemanovi\u0107 je zapo\u010dela program prakti\u010dnom radionicom o meta-analizi koriste\u0107i METAL<\/strong>. Nakon toga, Lucija Buljac<\/strong> je predstavila koncept Poligenih skorova rizika (PRS)<\/strong>. <\/p>\n\n

U\u010desnici su zatim primenili ovo znanje u praksi tokom kompjuterske radionice o PRS-u koriste\u0107i SBayesR i SBayesRC<\/strong>.<\/p>\n\n

Zavr\u0161no predavanje, koje su vodile Andrea Gelemanovi\u0107 i Nikolina Plei\u0107, istra\u017eivalo je Napredne genomske pristupe<\/strong>, uklju\u010duju\u0107i ma\u0161insko u\u010denje i Mendelovu randomizaciju.<\/p>\n\n

Letnja \u0161kola je zaklju\u010dena sesijom pitanja i odgovora, povratnim informacijama o kursu i zatvaranjem<\/strong>, pru\u017eaju\u0107i u\u010desnicima i predava\u010dima poslednju priliku za razmenu ideja i osvrt na petodnevni program.<\/p>\n\n

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Pet dana u\u010denja i saradnje<\/h2>\n\n

Druga letnja \u0161kola InnoThyroGen kombinovala je teorijsko znanje sa prakti\u010dnim iskustvom. U\u010desnici su razvili ve\u0161tine iz statistike, Linux-a, R-a, GWAS-a, kontrole kvaliteta, populacione strukture, analize asocijacije, funkcionalne anotacije, meta-analize i Poligenih skorova rizika. <\/p>\n\n

Jednako va\u017eno, Letnja \u0161kola je stvorila prostor za diskusiju, razmenu znanja i saradnju me\u0111u istra\u017eiva\u010dima zainteresovanim za genetiku i genomiku.<\/p>\n\n

Kroz aktivnosti kao \u0161to je Letnja \u0161kola, InnoThyroGen nastavlja da ja\u010da istra\u017eiva\u010dke kapacitete i razmenu znanja u genomici i personalizovanoj medicini.<\/strong><\/p>\n\n

\ud83d\udce2 Pratite nas za novosti, pratite na\u0161e kanale i ne propustite priliku da se pridru\u017eite slede\u0107oj Letnjoj \u0161koli InnoThyroGen!<\/p>\n\n

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\"\"<\/figure>\n<\/figure>\n","protected":false},"excerpt":{"rendered":"

Od 8. do 12. septembra 2026., projekat InnoThyroGen odr\u017eao je svoju 2. letnju \u0161kolu na Institutu za molekularnu genetiku i geneti\u010dko in\u017eenjerstvo (IMGGE) u Beogradu, Srbija. Tokom pet dana, u\u010desnici su istra\u017eivali klju\u010dne metode i alate koji se koriste u humanoj genetici i studijama asocijacije na nivou celog genoma (GWAS). Program je kombinovao predavanja, prakti\u010dne […]<\/p>\n","protected":false},"author":1,"featured_media":3071,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[47],"tags":[50,86,48,49,52,71,51],"class_list":["post-3027","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-47","tag-eufunded","tag-genetics","tag-horizoneurope","tag-innothyrogen","tag-personalisedmedicine","tag-pharmacogenomics","tag-thyroidhealth"],"yoast_head":"\nLetnja \u0161kola InnoThyroGen 2026 u Beogradu<\/title>\n<meta name=\"description\" content=\"Letnja \u0161kola InnoThyroGen 2026 u Beogradu okupila je u\u010desnike na petodnevnoj prakti\u010dnoj obuci iz GWAS-a, genomike, R-a, Linux-a i geneti\u010dke 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