{"id":2981,"date":"2026-09-14T14:39:34","date_gmt":"2026-09-14T14:39:34","guid":{"rendered":"https:\/\/www.innothyrogen.eu\/uncategorized-hr\/druga-ljetna-skola-innothyrogen-donosi-obuku-iz-genomike-i-gwas-a-u-beograd\/"},"modified":"2026-09-17T07:18:12","modified_gmt":"2026-09-17T07:18:12","slug":"druga-ljetna-skola-innothyrogen-donosi-obuku-iz-genomike-i-gwas-a-u-beograd","status":"publish","type":"post","link":"https:\/\/www.innothyrogen.eu\/hr\/vijesti\/druga-ljetna-skola-innothyrogen-donosi-obuku-iz-genomike-i-gwas-a-u-beograd\/","title":{"rendered":"Druga ljetna \u0161kola InnoThyroGen donosi obuku iz genomike i GWAS-a u Beograd"},"content":{"rendered":"\n

Od 8. do 12. rujna 2026.<\/strong>, projekt InnoThyroGen odr\u017eao je svoju 2. ljetnu \u0161kolu<\/strong> na Institutu za molekularnu genetiku i geneti\u010dko in\u017eenjerstvo (IMGGE<\/a>) u Beogradu, Srbija.<\/p>\n\n

Tijekom pet dana, sudionici su istra\u017eivali klju\u010dne metode i alate koji se koriste u ljudskoj genetici i studijama asocijacije na razini cijelog genoma (GWAS). Program je kombinirao predavanja, prakti\u010dne ra\u010dunalne radionice, pozvana predavanja, grupne rasprave i interaktivne sesije. <\/p>\n\n

Ljetna \u0161kola postupno je prelazila s temeljnih statisti\u010dkih i ra\u010dunalnih vje\u0161tina na napredne genomske analize. Sudionici su radili s alatima i metodama koje se koriste u modernim geneti\u010dkim istra\u017eivanjima i imali su mnogo prilika za raspravu o svom radu s predava\u010dima i drugim sudionicima. <\/p>\n\n

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1. dan \u2013 Izgradnja temelja<\/h2>\n\n

Ljetna \u0161kola zapo\u010dela je sesijom dobrodo\u0161lice i upoznavanja sudionika<\/strong>, koja je predstavila program i pru\u017eila sudionicima priliku da se me\u0111usobno upoznaju.<\/p>\n\n

Prva predavanja bila su usmjerena na statisti\u010dke osnove potrebne za geneti\u010dke studije. Nikolina Plei\u0107<\/a><\/strong> predstavila je klju\u010dne statisti\u010dke koncepte kroz dvodijelno predavanje Uvod u statistiku za geneti\u010dke studije<\/em>.<\/p>\n\n

Poslijepodne su sudionici pre\u0161li s teorije na prakti\u010dan rad. Andrea Gelemanovi\u0107<\/a><\/strong> vodila je dvije ra\u010dunalne radionice o Linuxu. Sesije su pokrile osnovno i naprednije kori\u0161tenje Linuxa te su pripremile sudionike za ra\u010dunalni rad planiran za sljede\u0107e dane. <\/p>\n\n

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2. dan \u2013 Ljudska genetika, GWAS i R<\/h2>\n\n

2. dan upoznao je sudionike s ljudskom genetikom i studijama asocijacije na razini cijelog genoma<\/strong>.<\/p>\n\n

Andrea Gelemanovi\u0107 otvorila je dan s Uvodom u ljudsku genetiku i GWAS<\/em>. Nikolina Plei\u0107 zatim je nastavila s dvije sesije o Statisti\u010dkim modelima za GWAS<\/em>. <\/p>\n\n

Sudionici su tako\u0111er oja\u010dali svoje prakti\u010dne vje\u0161tine analize podataka. Tijekom dvije ra\u010dunalne radionice, Andrea Gelemanovi\u0107 predstavila je R<\/strong>, od po\u010detnog postavljanja i tipova podataka do manipulacije i vizualizacije podataka. <\/p>\n\n

Dan je zavr\u0161io grupnom raspravom o otvorenoj znanosti, etici i metodolo\u0161kim zamkama u GWAS-u<\/strong>. Sesija je potaknula sudionike da gledaju izvan tehni\u010dke analize i razmotre \u0161ire metodolo\u0161ke i istra\u017eiva\u010dke izazove. <\/p>\n\n

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3. dan \u2013 Kontrola kvalitete i populacijska struktura<\/h2>\n\n

Tre\u0107i dan bio je usmjeren na va\u017ene korake koje istra\u017eiva\u010di provode prije i tijekom GWAS analiza.<\/p>\n\n

Nakon pozvanog predavanja Lennarta C. Karssena<\/strong> (PolyOmica<\/a>, Nizozemska), Andrea Gelemanovi\u0107 upoznala je sudionike s kontrolom kvalitete za GWAS<\/strong>. Sudionici su zatim primijenili te koncepte tijekom prakti\u010dne radionice koriste\u0107i PLINK 2.0<\/strong>. <\/p>\n\n

Poslijepodne je bilo usmjereno na populacijsku strukturu<\/strong>. Nikolina Plei\u0107 prvo je predstavila temu kroz predavanje, a zatim je vodila sudionike kroz prakti\u010dnu radionicu PLINK 2.0. <\/p>\n\n

Dan je zaklju\u010den predavanjem o analizi asocijacija<\/strong>, pripremaju\u0107i sudionike za naprednije analize 4. dana.<\/p>\n\n

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4. dan \u2013 Od analize asocijacija do funkcionalne anotacije<\/h2>\n\n

4. dan nastavljen je s naprednim GWAS metodama i njihovom prakti\u010dnom primjenom.<\/p>\n\n

Program je zapo\u010deo pozvanim predavanjem Maxima Freydina<\/strong> (King\u2019s College London<\/a>, Ujedinjeno Kraljevstvo). Sudionici su zatim radili na analizi asocijacija<\/strong> koriste\u0107i PLINK 2.0 i GEMMA pod vodstvom Nikoline Plei\u0107. <\/p>\n\n

Sljede\u0107a ra\u010dunalna radionica bila je usmjerena na funkcionalnu anotaciju<\/strong>. Sudionici su istra\u017eivali nekoliko \u0161iroko kori\u0161tenih alata i resursa, uklju\u010duju\u0107i COLOC, FUMA, GTEx i LocusZoom. <\/p>\n\n

Poslijepodne su pozvani \u010dlanovi sudjelovali u InnoThyroGen R&I laboratoriju<\/strong>. U me\u0111uvremenu, sudionici Ljetne \u0161kole imali su priliku istra\u017eiti Beograd kroz vo\u0111eni obilazak grada. <\/p>\n\n

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5. dan \u2013 Poligeni rezultati rizika i napredna genomika<\/h2>\n\n

Posljednji dan okupio je nekoliko naprednih pristupa u geneti\u010dkim istra\u017eivanjima.<\/p>\n\n

Andrea Gelemanovi\u0107 zapo\u010dela je program prakti\u010dnom radionicom o meta-analizi pomo\u0107u METAL-a<\/strong>. Nakon toga, Lucia Buljac<\/strong> predstavila je koncept poligenih rezultata rizika (PRS)<\/strong>. <\/p>\n\n

Sudionici su zatim primijenili to znanje u praksi tijekom ra\u010dunalne radionice o PRS-u koriste\u0107i SBayesR i SBayesRC<\/strong>.<\/p>\n\n

Zavr\u0161no predavanje, koje su vodile Andrea Gelemanovi\u0107 i Nikolina Plei\u0107, istra\u017eivalo je napredne genomske pristupe<\/strong>, uklju\u010duju\u0107i strojno u\u010denje i Mendelovu randomizaciju.<\/p>\n\n

Ljetna \u0161kola zaklju\u010dena je sesijom pitanja i odgovora, povratnim informacijama o te\u010daju i zatvaranjem<\/strong>, daju\u0107i sudionicima i predava\u010dima posljednju priliku za razmjenu ideja i promi\u0161ljanje o petodnevnom programu.<\/p>\n\n

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Pet dana u\u010denja i suradnje<\/h2>\n\n

Druga ljetna \u0161kola InnoThyroGen kombinirala je teorijsko znanje s prakti\u010dnim iskustvom. Sudionici su razvili vje\u0161tine u statistici, Linuxu, R-u, GWAS-u, kontroli kvalitete, populacijskoj strukturi, analizi asocijacija, funkcionalnoj anotaciji, meta-analizi i poligenim rezultatima rizika. <\/p>\n\n

Jednako va\u017eno, Ljetna \u0161kola stvorila je prostor za raspravu, razmjenu znanja i suradnju me\u0111u istra\u017eiva\u010dima zainteresiranima za genetiku i genomiku.<\/p>\n\n

Kroz aktivnosti poput Ljetne \u0161kole, InnoThyroGen nastavlja ja\u010dati istra\u017eiva\u010dke kapacitete i razmjenu znanja u genomici i personaliziranoj medicini.<\/strong><\/p>\n\n

\ud83d\udce2 Pratite nas za novosti, pratite na\u0161e kanale i ne propustite priliku pridru\u017eiti se sljede\u0107oj InnoThyroGen ljetnoj \u0161koli!<\/p>\n\n

FOTO<\/h2>\n\n
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\"\"<\/figure>\n<\/figure>\n","protected":false},"excerpt":{"rendered":"

Od 8. do 12. rujna 2026., projekt InnoThyroGen odr\u017eao je svoju 2. ljetnu \u0161kolu na Institutu za molekularnu genetiku i geneti\u010dko in\u017eenjerstvo (IMGGE) u Beogradu, Srbija. Tijekom pet dana, sudionici su istra\u017eivali klju\u010dne metode i alate koji se koriste u ljudskoj genetici i studijama asocijacije na razini cijelog genoma (GWAS). Program je kombinirao predavanja, prakti\u010dne […]<\/p>\n","protected":false},"author":1,"featured_media":3025,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[40],"tags":[43,85,41,42,45,60,44],"class_list":["post-2981","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-vijesti","tag-eufunded","tag-genetics","tag-horizoneurope","tag-innothyrogen","tag-personalisedmedicine","tag-pharmacogenomics","tag-thyroidhealth"],"yoast_head":"\nLjetna \u0161kola InnoThyroGen 2026 u Beogradu<\/title>\n<meta name=\"description\" content=\"Ljetna \u0161kola InnoThyroGen 2026 u Beogradu okupila je pet dana prakti\u010dne obuke iz GWAS-a, genomike, R-a, Linuxa i geneti\u010dke analize.\" \/>\n<meta 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